REQUEST FOR PROPOSALS: Accelerating DRUG DISCOVERY for Frontotemporal Degeneration
Research investigating the pathologic mechanisms underlying frontotemporal degeneration (FTD) and related disorders is advancing, creating new potential targets for drug discovery. The Alzheimer’s Drug Discovery Foundation (ADDF) and The Association for Frontotemporal Degeneration (AFTD) seek to accelerate and support drug discovery for FTD and related disorders through this Request for Proposals (RFP).
Priority areas for this program include: • Development of clinical, biochemical, or neuroimaging biomarkers to accelerate drug development and early diagnosis • High throughput screening in novel cellular assays relevant to FTD • Identification and in vitro testing of potentially disease modifying compounds or biologics, including medicinal chemistry refinement, ADME, toxicology, pharmacokinetics, and pharmacodynamics studies • Testing of lead compounds or biologics in a relevant model for preclinical proof of concept
Please note: this funding will not support applications for basic research
Mechanism(s) of Support: ADDF/AFTD will provide grants for one-year duration (up to $150,000 each) with the possibility of follow-on funding. Applications may be submitted by non-profit academic institutions and for-profit biotechnology companies, both public and private, worldwide. Please note that funding to biotechnology companies is typically made as a program-related investment.
APPLICATION PROCEDURE All letters of intent and applications must be submitted electronically at LINK: www.alzdiscovery.org -> http://www.alzdiscovery.org. The deadline date for applications is September 5, 2014. Submission of a Letter of Intent (LOI) is required prior to August 22, 2014. LOIs are reviewed on a rolling basis. For additional resources and access to relevant Contract Research Organizations (CROs), please visit ADDF ACCESS: LINK: http://www.alzdiscovery.org/research-and-grants/addf-access/ -> http://www.alzdiscovery.org/research-and-grants/addf-access/
For more information on this RFP and other open funding opportunities through the ADDF, visit our website: LINK: http://www.alzdiscovery.org/research-and-grants/request-for-proposal -> http://www.alzdiscovery.org/research-and-grants/request-for-proposal